ProGP417 (Putative Uncharacterized Protein)

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ProGP ID ProGP417 (Putative Uncharacterized Protein)
Validation Status Uncharacterized
Organism Information
Organism NameAcinetobacter baumannii ATCC 17978
Domain Bacteria
Classification Family: Moraxellaceae
Order: Pseudomonadales
Class: Gammaproteobacteria
Division or phylum: "Proteobacteria"
Taxonomic ID (NCBI) 400667
Genome Information
GenBank CP000521.1
EMBL CP018664.1
Organism Additional Information Acinetobacter baumannii is an opportunistic nosocomial pathogen infecting immunocompromised patients. It causes pneumonia, septicaemia, urinary tract infections and meningitis. There has been a rise in the multidrug-resistant as well as pandrug-resistant strains of the ?superbug?.
Gene Information
Gene NameA1S_3658
GenBank Gene Sequence CP000521.1
Protein Information
Protein NamePutative Uncharacterized Protein
NCBI RefSeq ABS90083
EMBL-CDSABS90083.1
Sequence length 47 AA
Subcellular LocationMembrane
Function Unknown
Glycosylation Status
Glycosylation Type O- (Ser/Thr) linked
Technique(s) used for Glycosylation DetectionZIC HILIC and Mass spectrometry (LTQ-Orbitrap Velos)
Glycan Information
Glycan Annotation Pentasaccharide β-GlcNAc3NAcA4OAc-4-(β-GlcNAc-6-)-α-Gal-6-β-Glc-3-β-GalNAc-S/T. β-GlcNAc3NAcA4OAcA is an O-acetylated derivative of glucuronic acid.
GlyTouCan G09064NU
Technique(s) used for Glycan Identification 1H:13C HSQC 2D NMR and mass spectrometry
Protein Glycosylation linked (PGL) gene(s)
OST Gene NamePglLAb
OST ProGT IDProGT55 (PglLAb)
Literature
ReferenceIwashkiw, J.A., Seper, A., Weber, B.S., Scott, N.E., Vinogradov, E., Stratilo, C., Reiz, B., Cordwell, S.J., Whittal, R., Schild, S. and Feldman, M.F., 2012. Identification of a general O-linked protein glycosylation system in Acinetobacter baumannii and its role in virulence and biofilm formation. PLoS pathogens, 8(6), p.e1002758.
Corresponding Author Mario F Feldman
ContactAlberta Glycomics Centre, Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada
ReferenceIwashkiw JA, Seper A, Weber BS, Scott NE, Vinogradov E, Stratilo C, Reiz B, Cordwell SJ, Whittal R, Schild S, Feldman MF. (2012) Identification of a general O-linked protein glycosylation system in Acinetobacter baumannii and its role in virulence and biofilm formation. PLoS Pathog., 8(6):e1002758. [PubMed: 22685409]
AuthorIwashkiw JA, Seper A, Weber BS, Scott NE, Vinogradov E, Stratilo C, Reiz B, Cordwell SJ, Whittal R, Schild S, Feldman MF.
Research GroupAlberta Glycomics Centre, Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada
Corresponding Author Feldman MF.
ContactAlberta Glycomics Centre, Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada