ProGP454 (Rv1887)
Home -> ProGPdb -> Search ProGP -> Display data
ProGP ID | ProGP454 (Rv1887) | ||||||||||||||||||||||||
Validation Status | Characterized | ||||||||||||||||||||||||
Organism Information | |||||||||||||||||||||||||
Organism Name | Mycobacterium tuberculosis H37Rv | ||||||||||||||||||||||||
Domain | Bacteria | ||||||||||||||||||||||||
Classification | Family: Mycobacteriaceae Suborder: Corynebacterineae Order: Actinomycetales Subclass: Actinobacteridae Class: Actinobacteria Division or phylum: "Actinobacteria" | ||||||||||||||||||||||||
Taxonomic ID (NCBI) | 83332 | ||||||||||||||||||||||||
Genome Information | |||||||||||||||||||||||||
GenBank | NC_000962.3 | ||||||||||||||||||||||||
EMBL | CP009480 | ||||||||||||||||||||||||
Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. | ||||||||||||||||||||||||
Gene Information | |||||||||||||||||||||||||
Gene Name | Rv1887 | ||||||||||||||||||||||||
NCBI Gene ID | 885247 | ||||||||||||||||||||||||
GenBank Gene Sequence | NC_000962.3 | ||||||||||||||||||||||||
Protein Information | |||||||||||||||||||||||||
Protein Name | Rv1887 | ||||||||||||||||||||||||
UniProtKB/SwissProt ID | O07745 | ||||||||||||||||||||||||
NCBI RefSeq | NP_216403.1" | ||||||||||||||||||||||||
EMBL-CDS | CCP44653.1. | ||||||||||||||||||||||||
UniProtKB Sequence | >tr|O07745|O07745_MYCTU Membrane protein OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=Rv1887 PE=1 SV=3 MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRNAQAIHTAEQLAAEVLLAHE VAAAGDHRLRVIGVTWNAEASAQAALLVESLTGAGFDNVVPVRRLRAIETLAQAIAPVIG YEQIAVCVLEHESATVVMVDTHDGKTQIAVKHVCRGLSGLTSWLTGMFGRDAWRPAGVVV VGSDSEVSEFSWQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVADSVSQPT VAPRRSRHYAGAAAALAAAAVTFVASLSLAVGIQLAPHNDTGTAKHGAHKPTPRIAKAVA PAVPPPPTVTPPVPARAPRPAAQHEPPARVTSGEALTEPNPPEEQPNASAPQQDRNDSQP ITRVLEHIPGAYGDSAPPAE | ||||||||||||||||||||||||
Sequence length | 380 AA | ||||||||||||||||||||||||
Subcellular Location | Membrane | ||||||||||||||||||||||||
Glycosylation Status | |||||||||||||||||||||||||
Glycosylation Type | O- (Thr) linked | ||||||||||||||||||||||||
Experimentally Validated Glycosite(s) in Full Length Protein | T308 and T310 | ||||||||||||||||||||||||
Glycosite(s) Annotated Protein Sequence | >tr|O07745|O07745_MYCTU Membrane protein OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=Rv1887 PE=1 SV=3 MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRNAQAIHTAEQLAAEVLLAHE VAAAGDHRLRVIGVTWNAEASAQAALLVESLTGAGFDNVVPVRRLRAIETLAQAIAPVIG YEQIAVCVLEHESATVVMVDTHDGKTQIAVKHVCRGLSGLTSWLTGMFGRDAWRPAGVVV VGSDSEVSEFSWQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVADSVSQPT VAPRRSRHYAGAAAALAAAAVTFVASLSLAVGIQLAPHNDTGTAKHGAHKPTPRIAKAVA PAVPPPPT*(308)VT*(310)PPVPARAPRPAAQHEPPARVTSGEALTEPNPPEEQPNASAPQQDRNDSQP ITRVLEHIPGAYGDSAPPAE | ||||||||||||||||||||||||
Sequence Around Glycosites (21 AA) | AVAPAVPPPPTVTPPVPARAP APAVPPPPTVTPPVPARAPRP | ||||||||||||||||||||||||
Average Amino Acid Composition around Glycosite(s) | _AVAPAVPPPPT(he)VT(he)PPVPAR__AVAPAVPPPPT(he)VT(he)PPVPAR_ | ||||||||||||||||||||||||
ProGP Web Logo | Technique(s) used for Glycosylation Detection | LC-MS (CID) | Technique(s) used for Glycosylated Residue(s) Detection | CID | Glycan Information | Glycan Annotation | Hex | Literature | Year of Identification | 2014 | Year of Identification Month Wise | 2014.1.31 | Reference | Smith GT, Sweredoski MJ, Hess S (2014) O-linked glycosylation sites profiling in Mycobacterium tuberculosis culture filtrate proteins.J Proteomics, 97:296-306. [PubMed: 23702328] | Author | Smith, Geoffrey T., Michael J. Sweredoski, and Sonja Hess. | Research Group | Proteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, CA, USA | Corresponding Author | Sonja Hess. | Contact | Proteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, CA, USA | |
---|