ProGP549 (Pilin A6)

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ProGP ID ProGP549 (Pilin A6)
Validation Status Uncharacterized
Organism Information
Organism NameHaloferax volcanii H53
Domain Archaea
Classification Family: Halobacteriaceae
Order: Halobacteriales
Class: Halobacteria or Halomebacteria
Division or phylum: "Euryarchaeota"
Taxonomic ID (NCBI) 309800
Genome Information
GenBank CP001955.1
EMBL CP001955.1
Gene Information
Gene NamepilA6 (HVO_A0633)
NCBI Gene ID 8923526
GenBank Gene Sequence NC_013966.1
Protein Information
Protein NamePilin A6
UniProtKB/SwissProt ID D4GRU1
NCBI RefSeq WP_004040986.1
EMBL-CDSADE02056.1
UniProtKB Sequence >tr|D4GRU1|D4GRU1_HALVD Pilin PilA OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) OX=309800 GN=pilA6 PE=4 SV=1 MQIKTMFTESRAVSPVIGVILMVAITVILAAVIGTFVLGLGDQVGDTAPQASFTFDYDGT ELTITHESGAQIDGDLVTIAGDVNVTDSSDANKWSTLGSDTISAGESVVVQDTDEDGFAN GDTVRVVWTSESGSNSATLQRWTYNA
Sequence length 146 AA
Function Structural subunit of type IV pili involved in surface adhesion
Glycosylation Status
Glycosylation Type N- (Asn) linked
ProGP Web Logo
Technique(s) used for Glycosylation DetectionAberrant migration on lithium dodecyl sulfate (LDS)-PAGE as detected through western blotting
Protein Glycosylation- Implication N-glycosylation may regulate the transition from planktonic cell to biofilm formation under stress conditions.
Protein Glycosylation linked (PGL) gene(s)
OST Gene NameAglB
Additional CommentPilin expression in ΔpilA[1–6]ΔaglB stimulates microcolony formation.
Literature
Year of Identification2016
Year of Identification Month Wise2016.05
ReferenceEsquivel, R.N., Schulze, S., Xu, R., Hippler, M. and Pohlschroder, M., 2016. Identification of Haloferax volcanii pilin N-glycans with diverse roles in pilus biosynthesis, adhesion, and microcolony formation. Journal of Biological Chemistry, 291(20), pp.10602-10614.
Corresponding Author Mechthild Pohlschroder
ContactFrom the Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 
ReferenceEsquivel RN, Schulze S, Xu R, Hippler M, Pohlschroder M. (2016) Identification of Haloferax volcanii Pilin N-Glycans with Diverse Roles in Pilus Biosynthesis, Adhesion, and Microcolony Formation. J Biol Chem., 291(20), 10602-14. [PubMed: 26966177]
AuthorEsquivel RN, Schulze S, Xu R, Hippler M, Pohlschroder M.
Research Group1 Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104. 2 Institute of Plant Biology and Biotechnology, University of Münster, Münster 48143, Germany. 3 Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Corresponding Author Pohlschroder M.
ContactDepartment of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104.