| ProGT ID | ProGT13.3 (WecB) |
| Organism Information | |
| Organism Name | Methanococcus maripaludis (strain S2 / LL) |
| Domain | Archaebacteria |
| Classification | Phylum : Euryarchaeota Class : Methanococci Orders : Methanococcales Family : Methanococcaceae Genus : Methanococcus Species : maripaludis Strain : S2 / LL |
| Taxonomic ID (NCBI) | 267377 |
| Genome Information | |
| Gene Bank | BX950229.1 |
| EMBL | BX950229.1 |
| Gene Information | |
| Gene Name | wecB |
| NCBI Gene ID | 2761897 |
| NCBI Reference Sequence | NC_005791.1. |
| Protein information | |
| Protein Name | WecB |
| UniProtKB/ SwissProt ID | Q6LZC4 |
| NCBI Ref Seq | WP_011170649.1. |
| UniProtKB Sequence | >sp|Q6LZC4|WECB_METMP UDP-N-acetylglucosamine 2-epimerase OS=Methanococcus maripaludis (strain S2 / LL) GN=wecB PE=1 SV=1 MYKIGIILGTRPEIIKMSPVIRELTTKKFFLIHTNQHYSENMDKIFFEELNLKKPDYNLN IGSGSHGDQTGRMLMEIEKVLLKEKPDFVLVQGDTNTVLAGALAASKLGIKIGHIEAGLR SFDRKMPEETNRVLTDHISEFLFAPTKTAANNILKEGISDEKIHIVGNTIVDATIQNLKI AEKNEKVCKFISKITKNEKYFLLTLHRAENTDNFEILSKLVTSINNISKKYEKNIIFPIH PRTHKKLNEFGLINKLENNHLIKIIEPVGYLEFLGLEKNAELIITDSGGLQEEACILNVP CVTLRENTERPETLDVNSNILAGSDPENILNCVEKMLKSNRHWNNPFGDGNSGKIIVNIV FGEKKP |
| EMBL CDS | CAF30261.1. |
| Sequence length | 366 AA |
| Subcellular Location | Cytoplasm |
| String | 267377.MMP0705. |
| Glycosylation Information | |
| CAZY Family | Non-GT |
| EC Number (BRENDA) | 5.1.3.14 |
| Acceptor Substrate Specificity | UDP-GlcNAc |
| Experimental Validation | In vitro |
| Product | UDP-ManNAc |
| Function in Glycosylation pathway | 1) The UDP-GlcNAc 2-epimerase catalyzes the isomerization of UDP-GlcNAc to produce UDP-ManNAc. |
| Additional Information | 1) The M. maripaludis WecB protein shares 36% amino acid identity with the E. coli UDP-GlcNAc 2-epimerase protein WecB, which is required for enterobacterial common-antigen biosynthesis. |
| Litrature | |
| Year Of Validation | 2008 |
| Reference | Namboori, S.C. and Graham, D.E., 2008. Acetamido sugar biosynthesis in the Euryarchaea. Journal of bacteriology, 190(8), pp.2987-2996. |
| Corresponding Author | Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA |