| ProGT ID | ProGT16.2 (AglH) |
| Organism Information | |
| Organism Name | Methanococcus voltae PS |
| Domain | Archaebacteria |
| Classification | Phylum : Euryarchaeota Class : Methanococci Orders : Methanococcales Family : Methanococcaceae Genus : Methanococcus Species : voltae Strain : PS |
| Taxonomic ID (NCBI) | 2188 |
| Genome Information | |
| Gene Bank | DQ372941.1 |
| EMBL | DQ372941.1 |
| Gene Information | |
| Gene Name | aglH |
| NCBI Reference Sequence | DQ372941 |
| Protein information | |
| Protein Name | AglH |
| Glycosylation Information | |
| Sugar Donor Specificity | UDP-GlcNAc |
| Acceptor Substrate Specificity | Dolichol-phosphate-disaccharide |
| Experimental Validation | In vivo |
| Donor Specificity | UDP-GlcNAc |
| Function in Glycosylation pathway | 1) AglH is a GlcNAc-1-P transferase involved in attachment of a GlcNAc residue to a dolichol lipid carrier in the membrane. |
| Additional Information | 1) Mv1751 is a GlcNAc-1-Phosphate transferase able to replaced the essential alg7 gene in S. cerevisiae. |
| Litrature | |
| Year Of Validation | 2008 |
| Reference | Shams-Eldin, H., Chaban, B., Niehus, S., Schwarz, R.T. and Jarrell, K.F., 2008. Identification of the archaeal alg7 gene homolog (encoding N-acetylglucosamine-1-phosphate transferase) of the N-linked glycosylation system by cross-domain complementation in Saccharomyces cerevisiae. Journal of Bacteriology, 190(6), pp.2217-2220. |
| Corresponding Author | Department of Microbiology and Immunology, Queens University, Kingston, Ontario, K7L 3N6, Canada. |
| Reference | Larkin, A., Chang, M.M., Whitworth, G.E. and Imperiali, B., 2013. Biochemical evidence for an alternate pathway in N-linked glycoprotein biosynthesis. Nature chemical biology, 9(6), pp.367-373. |
| Corresponding Author | Department of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel. |