ProGT ID | ProGT16.2 (AglH) |
Organism Information | |
Organism Name | Methanococcus voltae PS |
Domain | Archaebacteria |
Phylum | Euryarchaeota |
Classification | Family: Methanococcaceae Order: Methanococcales Class: Methanococci or Methanothermea Division or phylum: "Euryarchaeota" |
Taxonomic ID (NCBI) | 2188 |
Genome Information | |
Gene Bank | DQ372941 |
EMBL | DQ372941 |
Gene Information | |
Gene Name | aglHÂ |
NCBI Reference Sequence | DQ372941 |
Protein information | |
Protein Name | AglHÂ |
Glycosylation Information | |
Sugar Donor Specificity | UDP-GlcNAc |
Acceptor Substrate Specificity | Dolichol-phosphate-disaccharide |
Experimental Validation | In vivo |
Donor Specificity | UDP-GlcNAc |
Function in Glycosylation pathway | 1) AglH is a GlcNAc-1-P transferase involved in attachment of a GlcNAc residue to a dolichol lipid carrier in the membrane. |
Additional Information | 1) Mv1751 is a GlcNAc-1-Phosphate transferase able to replaced the essential alg7 gene in S. cerevisiae. |
Litrature | |
Year Of Validation | 2008Â |
Reference | Shams-Eldin H, Chaban B, Niehus S, Schwarz RT, Jarrell KF. (2008) Identification of the archaeal alg7 gene homolog (encoding N-acetylglucosamine-1-phosphate transferase) of the N-linked glycosylation system by cross-domain complementation in Saccharomyces cerevisiae. J Bacteriol. 190(6):2217-20. doi: 10.1128/JB.01778-07. |
Authors | Shams-Eldin H, Chaban B, Niehus S, Schwarz RT, Jarrell KF. |
Research groups | Institute for Virology, AG Parasitologie BMFZ, Philipps-University Marburg, Hans-Meerwein-Str. 2, 35043 Marburg, Germany. |
Contacts | Institute for Virology, AG Parasitologie BMFZ, Philipps-University Marburg, Hans-Meerwein-Str. 2, 35043 Marburg, Germany. |
Reference | Larkin, A., Chang, M. M., Whitworth, G. E., & Imperiali, B. (2013). Biochemical evidence for an alternate pathway in N-linked glycoprotein biosynthesis. Nature chemical biology, 9(6), 367. |
Authors | Larkin, A., Chang, M. M., Whitworth, G. E., & Imperiali, B. |
Research groups | Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. |
Corresponding Author | Imperiali, B. |
Contacts | Department of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel. |