| ProGT ID | ProGT25.1 (PglA) |
| Organism Information | |
| Organism Name | Neisseria meningitidis serogroup B (strain MC58) |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : Betaproteobacteria Orders : Neisseriales Family : Neisseriaceae Genus : Neisseria Species : meningitidis Strain : MC58 |
| Taxonomic ID (NCBI) | 122586 |
| Genome Information | |
| Gene Bank | AE002098.2 |
| EMBL | AE002098.2 |
| Gene Information | |
| Gene Name | pglA |
| NCBI Gene ID | 902330 |
| NCBI Reference Sequence | NC_003112.2. |
| Protein information | |
| Protein Name | PglA |
| UniProtKB/ SwissProt ID | Q9K1D9 |
| NCBI Ref Seq | WP_002221887.1. |
| UniProtKB Sequence | >tr|Q9K1D9|Q9K1D9_NEIMB Glycosyltransferase OS=Neisseria meningitidis serogroup B (strain MC58) GN=pglA PE=4 SV=1 MKIVFITTVASSIYGFRAPVIKKLIGKNHQVYAFVSEFSDNELDIIREMGVTPVTYRSNR SGLNPFSDIKSTFLIFKELKKISPDLVFPYFAKPVIFGTFAAKLAGVPRIVGMLEGLGFA FTPQPEGIPLKTKIIKGILIALYRIALPMLESLIVLNPDDKDELTDKYGIKIKNIHILGG IGLDLRQYPYSEADIPDEKEPVKFLFIGRFLKEKGIDDFIRAAEQVKDKYPDTVFTALGA IDKSRGGGGDLERLAARDIIRFPGFVNNVSEVIKEHHIFVLPSYYREGVPRSTQEAMAVG RAVITTDVPGCRETVADKVNGFLIEPWNPRILAEKMIYFIENREAVRLMGNASYAIAKDK FDAEKVDLKLLDILKA |
| EMBL CDS | AAF40674.1. |
| Sequence length | 376 AA |
| String | 122586.NMB0218. |
| Glycosylation Information | |
| CAZY Family | GT4 |
| EC Number (BRENDA) | 2.4.1.- |
| Sugar Donor Specificity | UDP-Galactose |
| Acceptor Substrate Specificity | Und-PP-diNAcBac |
| Experimental Validation | In vivo |
| Product | Und-PP-diNAcBac-Gal |
| Donor Specificity | UDP-Galactose |
| Function in Glycosylation pathway | 1) PglA is a glycosyltransferase responsible for the addition of galactose of the trisaccharide glycan in pilin modification. |
| Litrature | |
| Year Of Validation | 1998 |
| Reference | Jennings, M.P., Virji, M., Evans, D., Foster, V., Srikhanta, Y.N., Steeghs, L., Van Der Ley, P. and Moxon, E.R., 1998. Identification of a novel gene involved in pilin glycosylation in Neisseria meningitidis. Molecular microbiology, 29(4), pp.975-984. |
| Corresponding Author | Department of Microbiology, The University of Queensland, Brisbane, Australia. |