ProGT ID | ProGT29.2 (Gly) |
ProGT Pathway | |
Organism Information | |
Organism Name | Streptococcus parasanguinis FW213 |
Domain | Bacteria |
Classification | Phylum : Firmicutes Class : Bacilli Orders : Lactobacillales Family : Streptococcaceae Genus : Stretococcus Species : parasanguinis Strain : FW213 |
Taxonomic ID (NCBI) | 1114965 |
Genome Information | |
Gene Bank | CP003122.1 |
EMBL | CP003122.1 |
Gene Information | |
Gene Name | Gly |
Protein information | |
Protein Name | Gly |
UniProtKB/ SwissProt ID | I1ZPA3 |
NCBI Ref Seq | AFJ26877.1 |
UniProtKB Sequence | >tr|I1ZPA3|I1ZPA3_STRPA Putative glycosyltransferase (Gly) OS=Streptococcus parasanguinis FW213 GN=gly PE=4 SV=1 MIRRVMEKISVIIPAYNAEKYLEQCVESVRTQIYNNIEIIIVNDGSTDRTAEIIERLKEK DSRIRTLHKRINEGIGATRNSALELVTGQYILFLDSDDWIDPNHISDLYNLLVRTDSDVS IANFTRYIESDNRYEIHITDDDYYEQIFTPQEWFTYQYGKPHNLSLCFTVPWGKLYKRSL FDNILYYTGPFGEDDRTTWKLYLVADKIAYMHRSTMVYRVNGESLTQTTERSEVFSVEPV LERLALLSMLGFDLKNEIAAFDWRANLVKNISLANGNVELYKELQFQLNMIEKYRKN |
EMBL CDS | AFJ26877.1 |
Sequence length | 297 AA |
Glycosylation Information | |
CAZY Family | GT2 |
EC Number (BRENDA) | 2.4.99.18 |
Sugar Donor Specificity | UDP-Glucose or UDP-Galactose |
Experimental Validation | In vivo and In vitro |
Donor Specificity | UDP-Glucose or UDP-Galactose |
Additional Information | 1) Gly is a glucosyltransferase mediating the final step of Fap1 glycosylation. 2) Gly can transfer Glucose and Galactose, in vitro on Fap1 but it has higher activity toward transferring glucose. |
Litrature | |
Year Of Validation | 2009 |
Reference | Mistou, M.Y., Dramsi, S., Brega, S., Poyart, C. and Trieu-Cuot, P., 2009. Molecular dissection of the secA2 locus of group B Streptococcus reveals that glycosylation of the Srr1 LPXTG protein is required for full virulence. Journal of bacteriology, 191(13), pp.4195-4206. |
Corresponding Author | Institut Pasteur, Biological Unit of Gram-Positive Pathogenic Bacteria, URA CNRS 2172, Paris Cedex 15, France. |
Reference | Chaze, T., Guillot, A., Valot, B., Langella, O., Chamot-Rooke, J., Di Guilmi, A.M., Trieu-Cuot, P., Dramsi, S. and Mistou, M.Y., 2014. O-Glycosylation of the N-terminal region of the serine-rich adhesin Srr1 of Streptococcus agalactiae explored by mass spectrometry. Molecular & Cellular Proteomics, 13(9), pp.2168-2182. |
Corresponding Author | INRA, MICALIS UMR-1319, 78352 Jouy-en-Josas cedex, France |