ProGTNC15 (Short-chain dehydrogenase/reductase SDR)

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ProGT ID ProGTNC15 (Short-chain dehydrogenase/reductase SDR)
Organism Information
Organism NamePseudomonas aeruginosa PA7
Domain Bacteria
Classification Phylum : Proteobacteria
Class : Gammaproteobacteria
Orders : Pseudomonadales
Family : Pseudomanadaceae
Genus : Pseudomonas
Species : aeruginosa
Strain : PA7
Taxonomic ID (NCBI)381754
Genome Information
Gene BankCP000744.1
EMBLCP000744.1
Gene Information
Gene NamePSPA7_6249 
NCBI Reference SequenceCP000744
Protein information
Protein NameShort-chain dehydrogenase/reductase SDR 
UniProtKB/ SwissProt IDA6VES5
NCBI Ref SeqWP_012078026.1.
UniProtKB Sequence>tr|A6VES5|A6VES5_PSEA7 Short-chain dehydrogenase/reductase SDR OS=Pseudomonas aeruginosa (strain PA7) GN=PSPA7_6249 PE=4 SV=1 MKKILIVGATSAIAEATARRFAAQGATLLLLARDRERLQLLATDLEVRGAAAVHTLGFDA ATNNDYPVLVHSCIETLGGLDQVLIAHGTLSDQKACEQSVDLTLRELTINAFSVIALLTE LAKHFEAQNSGCIAVIGSVAGDRGRQSNYVYGTAKGALSLFLQGLRNRFGKSGVQVLTIK PGFVDTPMTAAFPKGPLWASPEKVAADIEKAIAKGRDVLYTPGFWLPIMVIIRLLPERLF KKLSL
EMBL CDSABR83255.1.
Sequence length245 AA
Subcellular LocationMembrane (Integral component of membrane)
Glycosylation Information
Experimental ValidationIn vivo
Additional Information1) Deletion of PSPA7_6249 gene show that it required for the D-araf biosynthesis, It deletion also leads to the poor twitching motility, and significantly fewer surface pili than the wild-type even in a retraction-deficient (pilT).  
Litrature
Year Of Validation2011 
Reference Harvey, H., Kus, J.V., Tessier, L., Kelly, J. and Burrows, L.L., 2011. Pseudomonas aeruginosa D-arabinofuranose biosynthetic pathway and its role in type IV pilus assembly. Journal of Biological Chemistry, 286(32), pp.28128-28137.

Corresponding AuthorMichael G DeGroote Institute for Infectious Diseases Research and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada.