| ProGT ID | ProGTNC5 (PseC) |
| Organism Information | |
| Organism Name | Helicobacter pylori 26695 |
| Domain | Bacteria |
| Phylum | Proteobacteria |
| Classification | Family: Helicobacteraceae Order: Campylobacterales Class: Epsilonproteobacteria Division or phylum: "Proteobacteria" |
| Taxonomic ID (NCBI) | 85962 |
| Genome Information | |
| Gene Bank | AE000511 |
| EMBL | AE000511 |
| Gene Information | |
| Gene Name | pseC |
| NCBI Gene ID | 899219 |
| Protein information | |
| Protein Name | PseC (HP_0366) |
| UniProtKB/ SwissProt ID | O25130 |
| NCBI Ref Seq | WP_000657303.1 |
| UniProtKB Sequence | >sp|O25130|PSEC_HELPY UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase OS=Helicobacter pylori (strain ATCC 700392 / 26695) OX=85962 GN=pseC PE=1 SV=1 MKEFAYSEPCLDKEDKKAVLEVLNSKQLTQGKRSLLFEEALCEFLGVKHALVFNSATSAL LTLYRNFSEFSADRNEIITTPISFVATANMLLESGYTPVFAGIKNDGNIDELALEKLINE RTKAIVSVDYAGKSVEVESVQKLCKKHSLSFLSDSSHALGSEYQNKKVGGFALASVFSFH AIKPITTAEGGAVVTNDSELHEKMKLFRSHGMLKKDFFEGEVKSIGHNFRLNEIQSALGL SQLKKAPFLMQKREEAALTYDRIFKDNPYFTPLHPLLKDKSSNHLYPILMHQKFFTCKKL ILESLHKRGILAQVHYKPIYQYQLYQQLFNTAPLKSAEDFYHAEISLPCHANLNLESVQN IAHSVLKTFESFKIE |
| EMBL CDS | AAD07433 |
| Sequence length | 375 AA |
| String | 85962.HP0366 |
| PDB ID (Structural Information) | 2FN6, 2FNI, 2FNU |
| Glycosylation Information | |
| EC Number (BRENDA) | 2.6.1.92 |
| Acceptor Substrate Specificity | UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose |
| Experimental Validation | In vitro |
| Product | UDP-4-amino-4,6-dideoxy-?-l-AltNAc |
| Function in Glycosylation pathway | 1) Aminotransferase activity, involved in the second step of the biosynthesis of pseudaminic acid. |
| Litrature | |
| Year Of Validation | 2005 |
| Reference | Schoenhofen, I.C., McNally, D.J., Vinogradov, E., Whitfield, D., Young, M., Dick, S., Wakarchuk, W.W., Brisson, J.R. & Logan, S. M. (2005). Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways. Journal of Biological Chemistry. |
| Authors | Schoenhofen, I.C., McNally, D.J., Vinogradov, E., Whitfield, D., Young, M., Dick, S., Wakarchuk, W.W., Brisson, J.R. & Logan, S. M. |
| Research groups | Institute for Biological Sciences, National Research Council, Ottawa, Ontario K1A OR6, Canada |
| Corresponding Author | Logan, S. M. |
| Contacts | Institute for Biological Sciences, National Research Council, Ottawa, Ontario K1A OR6, Canada |
| Reference | Schoenhofen IC, Lunin VV, Julien JP, Li Y, Ajamian E, Matte A, Cygler M, Brisson JR, Aubry A, Logan SM, Bhatia S. Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori. Journal of Biological Chemistry. 2006 Mar 31;281(13):8907-16. |
| Authors | Schoenhofen IC, Lunin VV, Julien JP, Li Y, Ajamian E, Matte A, Cygler M, Brisson JR, Aubry A, Logan SM, Bhatia S |
| Research groups | 1 Institute for Biological Sciences, National Research Council, Ottawa, Ontario K1A 0R6. |
| Corresponding Author | Bhatia S |
| Contacts | 1 Institute for Biological Sciences, National Research Council, Ottawa, Ontario K1A 0R6. |