ProGT119 (Maf)
ProGT ID | ProGT119 (Maf) |
Organism Information | |
Organism Name | Magnetospirillum magneticum AMB-1 |
Clinical Implication | Non-pathogenic |
Domain | Bacteria |
Classification | Phylum : Proteobacteria Class : AlphaProteobacteria Orders : Rhodospirillales Family : Rhodospirillaceaee Genus : Magnetospirillum Species : magneticum Strain : AMB-1 |
Taxonomic ID (NCBI) | 342108 |
Genome Information | |
Gene Bank | AP007255 |
EMBL | AP007255 |
Gene Information | |
Gene Name | amb0685 |
Protein information | |
Protein Name | Maf |
UniProtKB/ SwissProt ID | Q2W9I6 |
NCBI Ref Seq | WP_011383128.1? |
UniProtKB Sequence | >tr|Q2W9I6|Q2W9I6_MAGSA Uncharacterized protein OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) OX=342108 GN=amb0685 PE=1 SV=1 MAAAPQINAELVSAYLEAFLELMPEMGERLRVHRPQSNLVVNEDGDLDVEFRGEFLYGPG GRKRIEDMATRTALGPDHRISAAPLSSGHVDLIVKRFLYNILKRATDSGLSFLQHPEESG GFHMVCLGLGLGYQLPILLEQDNPAGIHIVEPNFDFLYHSLSTVDWRPLLETRRENPLRL NIIIEEEPGQIARQLRSAIRCCCPIVVDWTRLFVAYNSPLLTAAMSEFMRDAQLIGIGLG FLHDEMEMTRASYKNMRDGRYSILQHSATQLHTPVFIVGSGPSIDDDIEVIKANQDRAVI ISCGTASRVLLANGIQPDFQMLLENGAAPYRALAAVHEEFGFGSATLIGSNTVDPRVRDL FEDVVYYFRPALSSYALFSPGIEYSLDDSGPTVTNTGTTAALALGFRELYLFGVDLGSRN PKRHHSKQSLYRHADDTKDGQKGAMDFDAVFDVREPGNFGGVVYSETIMLWTRDALGRII GRYRPAANAFNCSDGVMIENTRPLSSQSLRLKSTPDMKAKDLAKVRASFRPGGEELFHDR WDREDWPRSIVTLLGECAQAMDDHVGDSNRLMLVLSEMLLRDYKQPPTVAQFFVRGTLMM AAMCYDYYVKRVTPADRKAEFWEIIRDEFHQMIRVMTLQVEWYFDNIEAFESDEELFDKV TGWDYD |
EMBL CDS | BAE49489.1 |
Sequence length | 666 AA |
Function in Native Organism | 1) Maf is involved in bacterial flagella glycosylation. |
String | 342108.amb0685 |
Potential Application | 1) 3D structure of Maf provides a structural template for the Maf family glycosyltransferases. 2) Structural studies may help the development of novel antibiotic agents specifically targeting these family pathogens. |
Additional Information | 1) Maf dependent glycosylation of flagellin with pseudaminic acid is important for the assembly and export of flagellum monomers. |
Glycosyltransferase Information | |
Glycosylation Type | O- (Ser/Thr) linked |
EC Number (BRENDA) | 2.4.1.- |
Mechanism of Glycan Transfer | Sequential |
Glycan Information | |
Glycan transferred | A nonulosonic acids sugar (most likely pseudaminic acid) |
Method of Glycan Indentification | LC-MS/MS |
Experimental_strategies | In vivo |
Acceptor Subtrate Information | |
Acceptor Substrate name | Flagella |
ProGPdb ID | ProGP682 |
Litrature | |
Year Of Validation | 2018 |
Reference | Sulzenbacher, G., Roig?Zamboni, V., Lebrun, R., Guérardel, Y., Murat, D., Mansuelle, P., Yamakawa, N., Qian, X.X., Vincentelli, R., Bourne, Y. and Wu, L.F., 2018. Glycosylate and move! The glycosyltransferase Maf is involved in bacterial flagella formation. Environmental microbiology, 20(1), pp.228-240. |
Corresponding Author | International Associated Laboratory of Evolution and Development of Magnetotactic Organisms (LIA-MagMC), Centre National de la Recherche Scientifique, Marseille 13402, France. |