ProGT85 (TfpOM2)

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ProGT ID ProGT85 (TfpOM2)
Organism Information
Organism NameAcinetobacter nosocomialis strain M2
Clinical ImplicationPathogenic
Classification Phylum : Proteobacteria
Class : GammaProteobacteria
Orders : Pseudomonadales
Family : Moraxellaceae
Genus : Acinetobacter
Species : nosocomialis
Strain : M2
Taxonomic ID (NCBI)1343071
Genome Information
Gene BankAPPP01000010 
Gene Information
Gene NametfpO
Protein information
Protein NameTfpOM2 
Subcellular LocationMembrane (Integral component of membrane)
Additional Information1) TfpOM2 is required for the glycosylation of pilA at its terminal serine residue.
2) The carboxy-terminal serine 136 of PilAM2 is modified by glycosyltransferase TfpOM2.
Glycosyltransferase Information
Glycosylation TypeO- (Ser/Thr) linked 
EC Number (BRENDA)2.4.1.-
Mechanism of Glycan TransferEn Bloc
Donor TypeUndPP-Tetrasaccharide
Donor SpecificityLipid linked sugars
Glycan Information
Glycan transferredTetrasaccharide containing (HexNAc)2, Monosaccharide ( hexose) and N-acetyl-deoxyMonosaccharide ( hexose) 
Method of Glycan IndentificationLC-MS, and MS-MS (CID and HCD)
Acceptor Subtrate Information
Acceptor Substrate name PilA
ProGPdb ID ProGP419
Year Of Validation2015 
Reference Harding, C.M., Nasr, M.A., Kinsella, R.L., Scott, N.E., Foster, L.J., Weber, B.S., Fiester, S.E., Actis, L.A., Tracy, E.N., Munson Jr, R.S. and Feldman, M.F., 2015. A cinetobacter strains carry two functional oligosaccharyltransferases, one devoted exclusively to type IV pilin, and the other one dedicated to O?glycosylation of multiple proteins. Molecular microbiology, 96(5), pp.1023-1041.

Corresponding AuthorDepartment of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2G2, Canada.